PENGARUH ASAM KLOROGENAT PADA KOPI HIJAU TERHADAP PENURUNAN BERAT BADAN WANITA OBESITAS

Main Article Content

Yanna Wari Harahap Wiwi Wardani Tanjung

Abstract

Kejadian Obesitas pada orang dewasa berusia >18 tahun di Indonesia mengalami peningkatan dari tahun 2007 sebanyak 10,5% menjadi 21,8% pada tahun 2018, di Wilayah Sumatera Utara kejadian obesitas pada tahun 2018 telah melebihi angka nasional yaitu 26,2%. Salah  satu  senyawa  aktif  yang  mampu  mengobati  obesitas,  yaitu  asam  klorogenat  yang merupakan salah satu terapi farmakologis yang bersumber dari kopi hijau. Penelitian ini bertujuan untuk menguji pengaruh dari asam klorogenat pada kopi hijau terhadap penurunan berat badan wanita obesitas. Desain penelitian yang digunakan yaitu kuasi eksperimen pada dua kelompok, dengan menggunakan uji statistik Wilcoxon. Hasil analisis menunjukkan terdapat perbedaan berat badan wanita obesitas sebelum dan sesudah diberikan ekstrak kopi hijau, dengan p-value 0,002. Rata-rata berat badan wanita obesitas mengalami penurunan sebelum dan sesudah diberikan ekstrak kopi hijau yaitu 67,6 Kg menjadi 63,5 Kg, sedangkan pada kelompok kontrol tidak mengalami perubahan yaitu 67,7 Kg pada wal penimbangan menjadi 67,8 Kg pada penimbangan berikutnya. Ekstrak kopi hijau merupakan salah satu alternatif yang dapat menurunkan berat badan secara farmakologis.

Article Details

How to Cite
[1]
Y. Harahap and W. Tanjung, “PENGARUH ASAM KLOROGENAT PADA KOPI HIJAU TERHADAP PENURUNAN BERAT BADAN WANITA OBESITAS”, JURNAL EDUCATION AND DEVELOPMENT, vol. 8, no. 1, p. 49, Jan. 2020.
Section
Artikel

References

Alhamhany, N. N. and Alassady, E. H. (2018) ‘Does green coffee has a positive effect on body mass index and lipid profile in a sample of obese people’, Journal of Pharmaceutical Sciences and Research, 10(3), pp. 627–630.
Chatterjee, B. (2005) ‘Green Coffee Bean Extract – Infuse Obesity’, International Journal of Innovative Research and Development, 4(11), pp. 237–239.
Cho, A. et al. (2010) ‘Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice’, Food and Chemical Toxicology. Elsevier Ltd, 48(3), pp. 937–943. doi: 10.1016/j.fct.2010.01.003.
Christopher, G. et al. (2018) The State of Obesity : Better Policies for a Helthier America 2018.
Flanagan, J. et al. (2014) ‘Lipolytic activity of svetol®, a decaffeinated green coffee bean extract’, Phytotherapy Research, 28(6), pp. 946–948. doi: 10.1002/ptr.5085.
Gorji, Z. et al. (2019) ‘The effect of green-coffee extract supplementation on obesity: A systematic review and dose-response meta-analysis of randomized controlled trials’, Phytomedicine, 63, p. 153018. doi: 10.1016/j.phymed.2019.153018.
Haidari, F. et al. (2017) ‘Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women’, 26(June 2016), pp. 1048–1054. doi: 10.6133/apjcn.022017.03.
Hausenblas, H. and Huynh, B. (2014) ‘Effects of Green Coffee Bean Extract on Weight Loss’, Journal of Pharmaceutical Sciences and Research, 6(3).
Kementerian Badan Penelitian dan Pengembangan Kesehatan (2018) Hasil Utama Riskesdas 2018 Kesehatan. Available at: Obesity is a harmful, costly, and complex health problem.
Li, S.-Y. et al. (2009) ‘Modulating Effects of Chlorogenic Acid on Lipids and Glucose Metabolism and Expression of Hepatic Peroxisome Proliferator-activated Receptor- Į in Golden Hamsters Fed on High Fat Diet 1’, Biomedical and environmental sciences, 129, pp. 122–129. doi: 10.1016/S0895-3988(09)60034-9.
Lim, J. U. et al. (2017) ‘Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients’, International Journal of COPD, 12, pp. 2465–2475. doi: 10.2147/COPD.S141295.
Madhava Naidu, M. et al. (2008) ‘Studies on extraction and antioxidant potential of green coffee’, Food Chemistry, 107(1), pp. 377–384. doi: 10.1016/j.foodchem.2007.08.056.
Murase, T. et al. (2011) ‘Coffee polyphenols suppress diet-induced body fat accumulation by downregulating SREBP-1c and related molecules in C57BL / 6J mice’. doi: 10.1152/ajpendo.00441.2010.
Nadimin, Ayumar and Fajarwati (2015) ‘Obesitas pada Orang Dewasa Anggota Keluarga Miskin di kecamatan Lembang Kabupaten Pinrang’, Jurnal MKMI, (September), pp. 9–15.
Onakpoya, I., Terry, R. and Ernst, E. (2011) ‘The use of green coffee extract as a weight loss supplement: A systematic review and meta-analysis of randomised clinical trials’, Gastroenterology Research and Practice, 2011. doi: 10.1155/2011/382852.
Ong, K. W. et al. (2012) ‘Chlorogenic Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation : A Contributor to the Beneficial Effects of Coffee on Diabetes’, Plose One, 7(3). doi: 10.1371/journal.pone.0032718.
Samadi, M., Mohammadshahi, M. and Haidari, F. (2015) ‘Operational definitions Methods Exclusion criteria’, Nutritional Disorder & Therapy, 5(4), pp. 1–3. doi: 10.4172/2161.
Sarriá, B. et al. (2016) ‘Long-term consumption of a green / roasted coffee blend positively affects glucose metabolism and insulin resistance in humans’, Food Research International. Elsevier Ltd, 89, pp. 1023–1028. doi: 10.1016/j.foodres.2015.12.032.
Shimoda, H., Seki, E. and Aitani, M. (2006) ‘Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice’, BMC Complementary and Alternative Medicine, 6(9), pp. 1–9. doi: 10.1186/1472-6882-6-9.
Sudikno (2010) ‘Hubungan Aktivitas Fisik dengan Kejadian Obesitas pada Orang Dewasa di Indonesia (Analisis Data Riskesdas 2007)’, Gizi Indonesia, 1(33), pp. 37–49.
Tanaka, K. et al. (2009) ‘Anti-obesity and hypotriglyceridemic properties of coffee bean extract in SD rats’, Food Science and Technology Research, 15(2), pp. 147–152. doi: 10.3136/fstr.15.147.
Yusaku, N. and Inouye, K. (2009) ‘Kinetic Analysis and Mechanism on the Inhibition of Chlorogenic Acid and Its Components against Porcine Pancreas r -Amylase Isozymes I and II’, Journal of Agricultural and Food Chemistry, 57(19), pp. 9218–9225. doi: 10.1021/jf9017383.
Zhao, Y. et al. (2012) ‘Antihypertensive effects and mechanisms of chlorogenic acids’, Hypertension Research. Nature Publishing Group, 35(4), pp. 370–374. doi: 10.1038/hr.2011.195.