KEAMANAN DAN EFEKTIVITAS MINYAK ZAITUN SEBAGAI TERAPI TOPIKAL DALAM MENGATASI PERADANGAN KULIT
Main Article Content
Abstract
Penelitian ini mengkaji efek terapi minyak zaitun terhadap peradangan kulit melalui tinjauan literatur. Minyak zaitun, yang telah lama digunakan dalam pengobatan tradisional, mengandung komponen bioaktif seperti asam oleat, polifenol (hidroksitirosol dan oleuropein), serta vitamin E, yang memiliki sifat anti-inflamasi, antioksidan, dan antimikroba. Metode penelitian yang digunakan adalah literature review, yang mengumpulkan dan menganalisis berbagai sumber relevan, termasuk artikel jurnal, buku, laporan penelitian, dan sumber online terpercaya. Hasil penelitian menunjukkan bahwa asam oleat dalam minyak zaitun dapat mengurangi produksi molekul pro-inflamasi, polifenol mampu menetralkan radikal bebas dan mengurangi stres oksidatif, sementara vitamin E melindungi sel-sel kulit dari kerusakan oksidatif dan mempercepat regenerasi jaringan kulit. Beberapa penelitian klinis dan pra-klinis mendukung efek anti-inflamasi minyak zaitun, menunjukkan pengurangan gejala peradangan seperti kemerahan, gatal, dan pembengkakan pada pasien dengan dermatitis atopik. Penelitian ini memberikan dasar yang kuat untuk penelitian lebih lanjut dan aplikasi klinis minyak zaitun sebagai terapi topikal yang aman dan efektif dalam mengatasi peradangan kulit. Dengan demikian, minyak zaitun adalah alternatif bahan alami yang menjanjikan untuk perawatan peradangan kulit
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M. Suryandari and A. Isdianto, “KEAMANAN DAN EFEKTIVITAS MINYAK ZAITUN SEBAGAI TERAPI TOPIKAL DALAM MENGATASI PERADANGAN KULIT”, JURNAL EDUCATION AND DEVELOPMENT, vol. 13, no. 1, pp. 43-51, May 2025.
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References
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Jiang, F., Wang, S., Han, D., Wei, J., Wu, Y., & Liu, Z. (2024). Glutamic‐acid grafted hyaluronic acid inhibits inflammatory factors via fibroblast and skin model tests. Skin Research and Technology, 30(1). https://doi.org/10.1111/srt.13548
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Leung, D. Y. (1999). Therapeutic perspectives in atopic dermatitis. Allergy, 54(s58), 39-42. https://doi.org/10.1111/j.1398-9995.1999.tb04748.x
Lim, K. M., Bae, S. H., Koo, J. E., Kim, E. S., Bae, O. N., & Lee, J. Y. (2014). Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester. Archives of Dermatological Research, 307(3), 219-227. https://doi.org/10.1007/s00403-014-1529-8
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Liu, T., He, Y., & Liao, Y. (2023). Esculentoside a ameliorates dncb‐induced atopic dermatitis by suppressing the ros‐nlrp3 axis via activating the nrf2 pathway. Clinical and Experimental Pharmacology and Physiology, 50(11), 844-854. https://doi.org/10.1111/1440-1681.13809
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Marrazzo, P. and O’Leary, C. (2020). Repositioning natural antioxidants for therapeutic applications in tissue engineering. Bioengineering, 7(3), 104. https://doi.org/10.3390/bioengineering7030104
Medina, E., Castro, A. d., Romero, C., & Brenes, M. (2006). Comparison of the concentrations of phenolic compounds in olive oils and other plant oils: correlation with antimicrobial activity. Journal of Agricultural and Food Chemistry, 54(14), 4954-4961. https://doi.org/10.1021/jf0602267
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